While AIDS may no longer dominate the headlines, the threat of HIV transmission persists. On World AIDS Day and every day, our mission remains the same: to empower you with the most advanced tools to stay protected. At Shanghai United Family Hospital (Changning), we offer comprehensive and confidential HIV prevention through Pre-Exposure Prophylaxis (PrEP) and Post-Exposure Prophylaxis (PEP).
PrEP (Pre-Exposure Prophylaxis)
PrEP is recommended for individuals who are HIV-negative and fall into higher-risk categories, such as:
• Individuals in a relationship with an HIV-positive partner.
• People who have multiple sexual partners.
• Those who do not consistently use condoms.
• People who share injection drug equipment.
• People who have been diagnosed with a sexually transmitted infection (STI) in the past 6 months.
• Anyone who wants to take control of their sexual health with a reliable, biomedical prevention method.
For years, the standard form of PrEP was a daily oral pill. The introduction of a long-acting injectable has given people a new choice, moving from a self-managed daily routine to a clinician-managed quarterly schedule. The availability of Apretude at Shanghai United Family Hospital since 2024 provides a convenient and highly effective new tool for individuals to proactively manage their sexual health.

Pill vs. Injection
| Feature | Daily Oral PrEP (Pill) | Long-Acting Injectable PrEP (Apretude) |
|---|---|---|
| Dosing Frequency | Every day | Every 2 months (after first 2 injections) |
| Administration | Self-administered at home | Administered by a healthcare professional |
| Adherence | Relies on daily habit | Built into the medical schedule |
| Effectiveness | >99% with perfect adherence | Highly effective; may be superior in real-world settings due to fewer adherence concerns. |
| Clinic Visits | Every 3 months for monitoring | Required for each injection (every 2 months) |
| Key Consideration | Remembering to take a daily pill | Committing to in-person injection appointments |
*Note: The best choice depends on your lifestyle and preference. Our doctors will help you decide which option is right for you.

PEP (Post-Exposure Prophylaxis)
PEP is a short course of emergency antiretroviral medicines taken after a possible exposure to HIV to prevent the virus from establishing an infection in the body.
• It is for emergencies only, not a substitute for regular prevention like PrEP (Pre-Exposure Prophylaxis).
• Time is critical: PEP must be started within 72 hours of a potential exposure, and the sooner you start it—ideally within 2 hours—the more effective it is.
• Effective Regimen: Our hospital provides the latest recommended PEP regimen, which is a single, once-daily pill containing Biktarvy (bictegravir, emtricitabine, and tenofovir alafenamide). This simplifies the treatment course and supports adherence.
The PEP Process at Shanghai United Family Hospital (Changning)
Our Emergency Department is designed for prompt, confidential, and efficient handling of such emergencies.
1. Seek Immediate Care
Come directly to our Emergency Department (ER) at any time, 24/7. Upon arrival, you can simply tell our staff:
"I need to see a doctor for a possible HIV exposure and PEP."
This will ensure you are directed to a private area quickly.
2. Immediate Risk Assessment & Counseling
Our doctor will speak with you privately to:
o Assess the level of risk of the exposure.
o Determine the time that has elapsed since the exposure.
o Counsel you on the benefits and potential side effects of PEP.
3. Required Baseline Testing
Before prescribing the medication, the doctor will conduct rapid tests to establish your baseline status, including:
o A rapid HIV test
o Tests for Hepatitis B and C
o Tests for other STIs and kidney/liver function (as needed)
4. Prescription and First Dose
If you are eligible, the doctor will prescribe a 28-day course of antiretroviral drugs.
The hospital pharmacy will dispense the medication, and you will often receive the first dose on-site.
5. Follow-up Appointments
You will be scheduled for follow-up visits at:
o 4 weeks: Side effects check and adherence support
o 3 months: Final HIV test to confirm treatment success

Key Advantages of Getting HIV Prevention at Shanghai United Family Hospital (Changning)
• International Standard of Care: Globally recognized protocols for PrEP and PEP.
• Confidentiality & Privacy: Consultations and medical records handled discreetly.
• Integrated One-stop Care: Consultation, lab, and pharmacy available on-site.
• Multilingual Staff: Accessible to both local and expatriate communities.
• Expert, Judgment-Free Care: Supportive, respectful environment.
Your Next Step to Protection
Whether you are considering proactive prevention with PrEP or need urgent care for a recent exposure with PEP, our team at Shanghai United Family Hospital is here for you.
Take the first step towards peace of mind today.
